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What is Lutetium Therapy?

Lutetium therapy, also known as Lutetium-177 therapy or Lutetium-177 dotatate therapy, is a targeted radionuclide therapy used for the treatment of certain types of neuroendocrine tumors, particularly those that express high levels of somatostatin receptors. It involves the administration of Lutetium-177, a radioactive isotope, combined with a somatostatin analog called dotatate, which binds to the somatostatin receptors on tumor cells. The radiation emitted by Lutetium-177 helps destroy the&

What is the Cost of Lutetium Therapy?

The cost of Lutetium Therapy is between Rs. 7,00,000 to Rs. 8,00,000 approximately.

Who is the Right Candidate for Lutetium Therapy?

Lutetium therapy is typically recommended for patients with advanced or metastatic neuroendocrine tumors, such as gastroenteropancreatic neuroendocrine tumors (GEP-NETs) and neuroendocrine tumors of the lungs (bronchial carcinoids), that show high levels of somatostatin receptor expression. A thorough evaluation by an oncologist or nuclear medicine specialist is necessary to determine if a patient is a suitable candidate for Lutetium therapy.

Technology Used in Lutetium Therapy:

Lutetium therapy involves the utilization of advanced nuclear medicine technology, including:

  • Radiopharmaceuticals: Lutetium-177 combined with dotatate is the radiopharmaceutical used in Lutetium therapy. The combination allows for targeted delivery of radiation to tumor cells that express somatostatin receptors.
  • Molecular Imaging: Imaging techniques such as somatostatin receptor scintigraphy (SRS) or positron emission tomography (PET) scans using somatostatin analogs labeled with radioactive tracers help in the diagnosis, staging, and selection of appropriate patients for Lutetium therapy.
  • Radiation Safety Measures: Proper radiation safety measures are implemented during the administration, handling, and disposal of Lutetium-177, ensuring the safety of healthcare professionals and minimizing radiation exposure to others.
Precautions After Lutetium Therapy:

After undergoing Lutetium therapy, it is important to take certain precautions to ensure safety and optimize treatment outcomes, such as:

  • Follow the specific instructions provided by the healthcare team regarding post-treatment care, including any dietary restrictions, activity limitations, and medication regimens.
  • Stay well-hydrated by drinking plenty of fluids to facilitate the elimination of the radioactive substance from the body.
  • Practi
Key Tests and Assessments After Lutetium Therapy:

Following Lutetium therapy, various tests and assessments may be performed to monitor treatment response, assess the overall health status, and manage any potential side effects. These may include:

  • Imaging studies, such as positron emission tomography (PET) scans or computed tomography (CT) scans, to evaluate tumor response and detect any signs of disease progression or recurrence.
  • Blood tests to monitor tumor markers, assess kidney and liver function, and evaluate blood cell counts.
  • Regular clinical assessments to monitor symptoms, overall well-being, and any treatment-related complications.

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Frequently Asked Questions

Yes, congenital heart disease can be passed down from a parent to a child. If one or both parents have a congenital heart defect, there is an increased risk of their child having the condition as well. However, it is important to note that not all congenital heart defects are inherited and some can occur due to other factors such as infections during pregnancy or exposure to certain medications or substances.

The initial treatment process for a child with congenital heart disorder depends on the type and severity of the condition. This could include medications for visible symptoms and monitoring with regular checkups.

The tests for congenital heart disorders do not always require hospitalization. Many of the tests can be performed on an outpatient basis, which means the patient can leave the hospital or clinic on the same day. However, some tests may require a short hospital stay, particularly if the patient is an infant or young child.

The treatment options for congenital heart disease may depend on the type and severity of the condition. These options may include medications or procedures like cardiac catheterization.